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Risk of Metachronous Colorectal Neoplasm After a Segmental Colectomy in Lynch Syndrome Patients According to Mismatch Repair Gene Status

BACKGROUND: Because of increased risk of metachronous colorectal cancer (CRC), all Lynch Syndrome (LS) patients are offered a total colectomy. However, since metachronous CRC rate by MMR gene is uncertain, and total colectomy negatively impacts quality of life, it remains unclear whether segmental r...

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Veröffentlicht in:J Am Coll Surg
Hauptverfasser: Quezada-Diaz, Felipe F, Hameed, Irbaz, von Mueffling, Alexa, Salo-Mullen, Erin E, Catalano, John D, Smith, J Joshua, Weiser, Martin R, Garcia-Aguilar, Julio, Stadler, Zsofia K, Guillem, Jose G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104918/
https://ncbi.nlm.nih.gov/pubmed/32007537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2020.01.005
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