IL-4 Alleviates Ischaemia-Reperfusion Injury by Inducing Kupffer Cells M2 Polarization via STAT6-JMJD3 Pathway after Rat Liver Transplantation

BACKGROUND: Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. METHODS: Donor livers were infused with recombinant IL-4 or normal saline during cold storage, and the he...

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Udgivet i:Biomed Res Int
Main Authors: Deng, Minghua, Wang, Jingyuan, Wu, Hao, Wang, Menghao, Cao, Ding, Li, Jinzheng, Wu, Yakun, Gong, Jianping
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104314/
https://ncbi.nlm.nih.gov/pubmed/32258110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2953068
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