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Stochastic activation and bistability in a Rab GTPase regulatory network

The eukaryotic endomembrane system is controlled by small GTPases of the Rab family, which are activated at defined times and locations in a switch-like manner. While this switch is well understood for an individual protein, how regulatory networks produce intracellular activity patterns is currentl...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Bezeljak, Urban, Loya, Hrushikesh, Kaczmarek, Beata, Saunders, Timothy E., Loose, Martin
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104049/
https://ncbi.nlm.nih.gov/pubmed/32161136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921027117
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