Loading...

Reversal of obesity and liver steatosis in mice via inhibition of aryl hydrocarbon receptor and altered gene expression of CYP1B1, PPARα, SCD1, and osteopontin

BACKGROUND/OBJECTIVES: Obesity is a global epidemic and the underlying basis for numerous comorbidities. We report that the aryl hydrocarbon receptor (AHR) plays a key role in the metabolism of obesity. The AHR is a promiscuous, ligand-activated nuclear receptor primarily known for regulating genes...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Obes (Lond)
Main Authors: Rojas, Itzel Y., Moyer, Benjamin J., Ringelberg, Carol S., Tomlinson, Craig R.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103522/
https://ncbi.nlm.nih.gov/pubmed/31911663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-019-0512-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!