Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice

BACKGROUND & AIMS: Trehalose is a disaccharide that might be used in treatment of cardiometabolic diseases. However, trehalose consumption promotes expansion of Clostridioides difficile ribotypes that metabolize trehalose via trehalose-6-phosphate hydrolase (treA). Furthermore, brush border and...

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Udgivet i:Gastroenterology
Main Authors: Zhang, Yiming, Shaikh, Nurmohammad, Ferey, Jeremie L., Wankhade, Umesh D., Chintapalli, Sree V., Higgins, Cassandra B., Crowley, Jan R., Heitmeier, Monique R., Stothard, Alicyn I., Mihi, Belgacem, Good, Misty, Higashiyama, Takanobu, Swarts, Benjamin M., Hruz, Paul W., Shankar, Kartik, Tarr, Phillip I., DeBosch, Brian J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103499/
https://ncbi.nlm.nih.gov/pubmed/31838076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.11.295
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