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Formation of stable homodimer via the C-terminal α-helical domain of coronavirus nonstructural protein 9 is critical for its function in viral replication

Coronaviruses devote more than three quarters of their coding capacity to encode two large polyproteins (1a and 1ab polyproteins), which are proteolytically processed into 15–16 mature, nonstructural replicase proteins (nsp1 to 16). These cleavage products are believed to play essential roles in rep...

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Detalles Bibliográficos
Publicado en:Virology
Main Authors: Chen, Bo, Fang, Shouguo, Tam, James P., Liu, Ding Xiang
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Inc. 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103386/
https://ncbi.nlm.nih.gov/pubmed/19022466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.10.032
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