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Mutational analysis of a helicase motif-based RNA 5′-triphosphatase/NTPase from bamboo mosaic virus

The helicase-like domain of BaMV replicase possesses NTPase and RNA 5′-triphosphatase activities. In this study, mutational effects of the helicase signature motifs and residue L543 on the two activities were investigated. Either activity was inactivated by K643A-S644A, D702A, D730A, R855A, or L543P...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Han, Yu-Tsung, Tsai, Chia-Sheng, Chen, Ya-Chio, Lin, Ming-Kuem, Hsu, Yau-Heiu, Meng, Menghsiao
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103348/
https://ncbi.nlm.nih.gov/pubmed/17585982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.05.013
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