Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognition

Many viruses encode antagonists to prevent interferon (IFN) induction. Infection of fibroblasts with the murine hepatitis coronavirus (MHV) and SARS-coronavirus (SARS-CoV) did not result in nuclear translocation of interferon-regulatory factor 3 (IRF3), a key transcription factor involved in IFN ind...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Versteeg, Gijs A., Bredenbeek, Peter J., van den Worm, Sjoerd H.E., Spaan, Willy J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2007
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103335/
https://ncbi.nlm.nih.gov/pubmed/17316733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.01.020
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