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Clinical Correlation of miR-200c/141 Cluster DNA Methylation and miR-141 Expression with the Clinicopathological Features of Colorectal Primary Lesions/Tumors

BACKGROUND: Abnormal DNA methylation leading to altered transcription of certain genes occurs frequently in colorectal cancer (CRC). As with protein-coding genes, microRNAs (miRNAs) may be targeted for methylation in CRC; however, the methylation state of miRNA genes in CRC, especially in primary le...

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Bibliografische gegevens
Gepubliceerd in:Rep Biochem Mol Biol
Hoofdauteurs: Taheri, Zahra, Asadzadeh Aghdaei, Hamid, Irani, Shiva, Modarressi, Mohammad Hossein, Noormohammadi, Zahra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Varastegan Institute for Medical Sciences 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103083/
https://ncbi.nlm.nih.gov/pubmed/32274392
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