Overexpression of enhance of Zeste homolog 2 (EZH2) in endometrial carcinoma: An NRG Oncology/Gynecologic Oncology Group Study

OBJECTIVES: Enhancer of zeste homolog 2 (EZH2) is a histone methyl transferase that mediates epigenetic silencing of tumor suppressor genes. It is commonly over-expressed in several solid tumors and has been shown to be a prognostic biomarker. We investigated patterns of EZH2 expression in endometri...

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Pubblicato in:Gynecol Oncol
Autori principali: Krill, Lauren, Deng, Wei, Eskander, Ramez, Mutch, David, Zweizig, Susan, Hoang, Bang, Ioffe, Olga, Randall, Leslie, Lankes, Heather, Miller, David S., Birrer, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103063/
https://ncbi.nlm.nih.gov/pubmed/31843273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.12.003
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