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Inhibition of viral RNA polymerases by nucleoside and nucleotide analogs: therapeutic applications against positive-strand RNA viruses beyond hepatitis C virus

A number of important human infections are caused by positive-strand RNA viruses, yet almost none can be treated with small molecule antiviral therapeutics. One exception is the chronic infection caused by hepatitis C virus (HCV), against which new generations of potent inhibitors are being develope...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Deval, Jerome, Symons, Julian A, Beigelman, Leo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102778/
https://ncbi.nlm.nih.gov/pubmed/25194816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2014.08.004
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