Ischemic Postconditioning Alleviates Intestinal Ischemia-Reperfusion Injury by Enhancing Autophagy and Suppressing Oxidative Stress through the Akt/GSK-3β/Nrf2 Pathway in Mice

AIMS: Ischemic postconditioning (IPO) has a strong protective effect against intestinal ischemia-reperfusion (IIR) injury that is partly related to autophagy. However, the precise mechanisms involved are unknown. METHODS: C57BL/6J mice were subjected to unilateral IIR with or without IPO. After 45 m...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Chen, Rong, Zhang, Yun-yan, Lan, Jia-nan, Liu, Hui-min, Li, Wei, Wu, Yang, Leng, Yan, Tang, Ling-hua, Hou, Jia-bao, Sun, Qian, Sun, Tao, Zeng, Zi, Xia, Zhong-yuan, Meng, Qing-tao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102478/
https://ncbi.nlm.nih.gov/pubmed/32256957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6954764
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