Feasibility of conditioning with thymoglobulin and reduced intensity TBI to reduce acute GVHD in recipients of allogeneic SCT

Murine studies using anti-T-cell antibodies for conditioning in allogeneic SCT demonstrate engraftment with low rates of GVHD. On the basis of this preclinical model, we conditioned 30 patients with advanced hematologic malignancies with rabbit antithymocyte globulin (ATG) and TBI, to reduce rates o...

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Publicat a:Bone Marrow Transplant
Autors principals: Toor, A, Rodriguez, T, Bauml, M, Mathews, H, Shanti, S, Senitzer, D, Kini, A, Norton, J, Parthasarathy, M, Mohideen, N, Petrowsky, C, Bonilla, B, Smith, S, Stiff, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101790/
https://ncbi.nlm.nih.gov/pubmed/18711352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2008.244
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