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Preventive effect of fluvastatin on the development of medication-related osteonecrosis of the jaw

Medication-related osteonecrosis of the jaw (MRONJ) occurs in patients undergoing oral surgery while medicated with bisphosphonate, denosumab or anti-angiogenic agents. We employed a MRONJ-like rat model to investigate whether injecting fluvastatin at extraction sites prevents MRONJ-like lesion. A M...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Adachi, Naomi, Ayukawa, Yasunori, Yasunami, Noriyuki, Furuhashi, Akihiro, Imai, Mikio, Sanda, Koma, Atsuta, Ikiru, Koyano, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101417/
https://ncbi.nlm.nih.gov/pubmed/32221325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61724-6
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