A bivalent vaccine confers immunogenicity and protection against Shigella flexneri and enterotoxigenic Escherichia coli infections in mice

Vaccine studies for Shigella flexneri and enterotoxigenic Escherichia coli have been impaired by the lack of optimal animal models. We used two murine models to show that a S. flexneri 2a bivalent vaccine (CVD 1208S-122) expressing enterotoxigenic Escherichia coli colonization factor antigen-I (CFA/...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:NPJ Vaccines
Main Authors: Medeiros, Pedro Henrique Q. S., Bolick, David T., Ledwaba, Solanka E., Kolling, Glynis L., Costa, Deiziane V. S., Oriá, Reinaldo B., Lima, Aldo Ângelo M., Barry, Eileen M., Guerrant, Richard L.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101394/
https://ncbi.nlm.nih.gov/pubmed/32257392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0180-y
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