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Changes in plasma arylsulfatase A level as a compensatory biomarker of early Parkinson’s disease

Lysosomal dysfunction has been associated with Parkinson’s disease (PD). However, the activity of lysosomal enzymes is heterogeneously observed in PD. We investigated whether arylsulfatase A (ARSA) level can be used as a fluid biomarker of PD and can reflect disease progression. Plasma ARSA level wa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Yoo, Han Soo, Lee, Jun Sung, Chung, Seok Jong, Ye, Byoung Seok, Sohn, Young H., Lee, Seung-Jae, Lee, Phil Hyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101326/
https://ncbi.nlm.nih.gov/pubmed/32221382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62536-4
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