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Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies
Differential expression (DE) analysis and gene set enrichment (GSE) analysis are commonly applied in single cell RNA sequencing (scRNA-seq) studies. Here, we develop an integrative and scalable computational method, iDEA, to perform joint DE and GSE analysis through a hierarchical Bayesian framework...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7101316/ https://ncbi.nlm.nih.gov/pubmed/32221292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15298-6 |
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