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Type II Non-ribosomal Peptide Synthetase Proteins: Structure, Mechanism, and Protein-Protein Interactions

Many medicinally-relevant compounds are derived from non-ribosomal peptide synthetase (NRPS) products. Type I NRPSs are organized into large modular complexes, while type II NRPS systems contain standalone or minimal domains that often encompass specialized tailoring enzymes that produce bioactive m...

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Detalhes bibliográficos
Publicado no:Nat Prod Rep
Main Authors: Jaremko, Matt J., Davis, Tony D., Corpuz, Joshua C., Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101270/
https://ncbi.nlm.nih.gov/pubmed/31593192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9np00047j
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