Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles

Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a wide range of biomedical applications, but there are many challenges facing its therapeutic use in vivo. Here, we report on a platelet cell membrane–coated metal-organic framework (MOF) nanodelivery platform...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Zhuang, Jia, Gong, Hua, Zhou, Jiarong, Zhang, Qiangzhe, Gao, Weiwei, Fang, Ronnie H., Zhang, Liangfang
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101224/
https://ncbi.nlm.nih.gov/pubmed/32258408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz6108
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