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Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles

Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a wide range of biomedical applications, but there are many challenges facing its therapeutic use in vivo. Here, we report on a platelet cell membrane–coated metal-organic framework (MOF) nanodelivery platform...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zhuang, Jia, Gong, Hua, Zhou, Jiarong, Zhang, Qiangzhe, Gao, Weiwei, Fang, Ronnie H., Zhang, Liangfang
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101224/
https://ncbi.nlm.nih.gov/pubmed/32258408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz6108
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