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The structure of the cohesin ATPase elucidates the mechanism of SMC–kleisin ring opening

Genome regulation requires control of chromosomal organization by SMC–kleisin complexes. The cohesin complex contains the Smc1 and Smc3 subunits which associate with the kleisin Scc1 to form a ring-shaped complex that can topologically engage chromatin to regulate chromatin structure. Release from c...

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Publicat a:Nat Struct Mol Biol
Autors principals: Muir, Kyle W., Li, Yan, Weis, Felix, Panne, Daniel
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100847/
https://ncbi.nlm.nih.gov/pubmed/32066964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0379-7
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