Resolvin D1 suppresses pannus formation via decreasing connective tissue growth factor caused by upregulation of miRNA-146a-5p in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and joint stiffness, finally leading to tissue destruction. Connective tissue growth factor (CTGF) is a critical factor in RA progression, which promotes fibroblast-like synoviocyte (FLS) proliferatio...

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Detalles Bibliográficos
Publicado en:Arthritis Res Ther
Main Authors: Sun, Weiwei, Ma, Jinglan, Zhao, Han, Xiao, Chipeng, Zhong, Hao, Ling, Hanzhi, Xie, Zhen, Tian, Qingqing, Chen, Huaijun, Zhang, Tingting, Chen, Mu, Jin, Shengwei, Wang, Jianguang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099804/
https://ncbi.nlm.nih.gov/pubmed/32216830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-2133-2
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