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Differential kidney proximal tubule cell responses to protein overload by albumin and its ligands
Albuminuria is frequently associated with proximal tubule (PT) cytotoxicity that can feed back to cause glomerular damage and exacerbate kidney disease. PT cells express megalin and cubilin receptors that bind to and internalize albumin over a broad concentration range. How the exposure to high conc...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7099508/ https://ncbi.nlm.nih.gov/pubmed/32068462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00490.2019 |
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