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Myocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis

Activation of hepatic stellate cells (HSCs), characterized by development of a robust actin cytoskeleton and expression of abundant extracellular matrix (ECM) proteins, such as type 1 collagen (COL.1), is a central cellular and molecular event in liver fibrosis. It has been demonstrated that HSCs ex...

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Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Main Authors: Shi, Zengdun, Ren, Mudan, Rockey, Don C.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099496/
https://ncbi.nlm.nih.gov/pubmed/31928221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00302.2019
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