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Platelet glycolytic metabolism correlates with hemodynamic severity in pulmonary arterial hypertension

Group 1 pulmonary hypertension (PH), i.e., pulmonary arterial hypertension (PAH), is associated with a metabolic shift favoring glycolysis in cells comprising the lung vasculature as well as skeletal muscle and right heart. We sought to determine whether this metabolic switch is also detectable in c...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: McDowell, Ruth E., Aulak, Kulwant S., Almoushref, Allaa, Melillo, Celia A., Brauer, Brittany E., Newman, Jennie E., Tonelli, Adriano R., Dweik, Raed A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099433/
https://ncbi.nlm.nih.gov/pubmed/32022593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00389.2019
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