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Effect of Lipidation on the Localization and Activity of a Lysozyme Inhibitor in Neisseria gonorrhoeae

The Gram-negative pathogen Neisseria gonorrhoeae (gonococcus [Gc]) colonizes lysozyme-rich mucosal surfaces. Lysozyme hydrolyzes peptidoglycan, leading to bacterial lysis. Gc expresses two proteins, SliC and NgACP, that bind and inhibit the enzymatic activity of lysozyme. SliC is a surface-exposed l...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Ragland, Stephanie A., Gray, Mary C., Melson, Elizabeth M., Kendall, Melissa M., Criss, Alison K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099142/
https://ncbi.nlm.nih.gov/pubmed/32041800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00633-19
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