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A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo

Near-infrared (NIR) fluorescent probes are among the most attractive chemical tools for biomedical imaging. However, their in vivo applications are hindered by albumin binding, generating unspecific fluorescence that masks the specific signal from the analyte. Here, combining experimental and dockin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Xing, Panfei, Niu, Yiming, Mu, Ruoyu, Wang, Zhenzhen, Xie, Daping, Li, Huanling, Dong, Lei, Wang, Chunming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099068/
https://ncbi.nlm.nih.gov/pubmed/32218438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15323-8
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