Rapid Molecular Response to Dasatinib in a Pediatric Relapsed Acute Lymphoblastic Leukemia With NCOR1-LYN Fusion

Background: Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is associated with high rates of treatment failure and poor outcome. Activation of ABL/Src family kinases is found in ~10% of Ph-like ALL, which can be therapeutically targeted by tyrosine kinase inhibitors. LYN is a...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Dai, Hai-Ping, Yin, Jia, Li, Zheng, Yang, Chun-Xiao, Cao, Tin, Chen, Ping, Zong, Yun-Hui, Zhu, Ming-Qing, Zhu, Xia-Ming, Xiao, Sheng, Wu, De-Pei, Tang, Xiao-Wen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098965/
https://ncbi.nlm.nih.gov/pubmed/32266142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00359
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