Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage

Using bacteriophage-derived endolysins as an alternative strategy for fighting drug-resistant bacteria has recently been garnering renewed interest. However, their application is still hindered by their narrow spectra of activity. In our previous work, we demonstrated that the endolysin LysIME-EF1 p...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Zhou, Biao, Zhen, Xiangkai, Zhou, Huan, Zhao, Feiyang, Fan, Chenpeng, Perčulija, Vanja, Tong, Yigang, Mi, Zhiqiang, Ouyang, Songying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098653/
https://ncbi.nlm.nih.gov/pubmed/32176738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008394
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