DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

BACKGROUND: DNA methylation outlier burden has been suggested as a potential marker of biological age. An outlier is typically defined as DNA methylation levels at any one CpG site that are three times beyond the inter-quartile range from the 25th or 75th percentiles compared to the rest of the popu...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Seeboth, Anne, McCartney, Daniel L., Wang, Yunzhang, Hillary, Robert F., Stevenson, Anna J., Walker, Rosie M., Campbell, Archie, Evans, Kathryn L., McIntosh, Andrew M., Hägg, Sara, Deary, Ian J., Marioni, Riccardo E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098133/
https://ncbi.nlm.nih.gov/pubmed/32216821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00838-0
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