Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

BACKGROUND: Osteoporosis is a complex disease with a strong genetic contribution. A recently published genome-wide association study (GWAS) for estimated bone mineral density (eBMD) identified 1103 independent genome-wide significant association signals. Most of these variants are non-coding, sugges...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Mullin, Benjamin H., Tickner, Jennifer, Zhu, Kun, Kenny, Jacob, Mullin, Shelby, Brown, Suzanne J., Dudbridge, Frank, Pavlos, Nathan J., Mocarski, Edward S., Walsh, John P., Xu, Jiake, Wilson, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098081/
https://ncbi.nlm.nih.gov/pubmed/32216834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01997-2
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