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Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond
In less than 20 years, the first selective type 5 phosphodiesterase inhibitor, sildenafil, has evolved from a potential anti-angina drug to an on-demand oral treatment for erectile dysfunction (Viagra), and more recently to a new orally active treatment for pulmonary hypertension (Revatio). Here we...
Enregistré dans:
| Publié dans: | Nat Rev Drug Discov |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7097805/ https://ncbi.nlm.nih.gov/pubmed/16883306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2030 |
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