Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection

Severe acute respiratory syndrome (SARS) is caused by infection of a previously undescribed coronavirus (CoV). L-SIGN, encoded by CLEC4M (also known as CD209L), is a SARS-CoV binding receptor that has polymorphism in its extracellular neck region encoded by the tandem repeat domain in exon 4. Our ge...

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Udgivet i:Nat Genet
Main Authors: Chan, Vera S F, Chan, Kelvin Y K, Chen, Yongxiong, Poon, Leo L M, Cheung, Annie N Y, Zheng, Bojian, Chan, Kwok-Hung, Mak, William, Ngan, Hextan Y S, Xu, Xiaoning, Screaton, Gavin, Tam, Paul K H, Austyn, Jonathan M, Chan, Li-Chong, Yip, Shea-Ping, Peiris, Malik, Khoo, Ui-Soon, Lin, Chen-Lung S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097088/
https://ncbi.nlm.nih.gov/pubmed/16369534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1698
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