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From empiricism to rational design: a personal perspective of the evolution of vaccine development

Vaccination, which is the most effective medical intervention that has ever been introduced, originated from the observation that individuals who survived a plague or smallpox would not get the disease twice. To mimic the protective effects of natural infection, Jenner — and later Pasteur — inoculat...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: De Gregorio, Ennio, Rappuoli, Rino
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096907/
https://ncbi.nlm.nih.gov/pubmed/24925139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3694
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