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A non-proliferative role of pyrimidine metabolism in cancer
BACKGROUND: Nucleotide metabolism is a critical pathway that generates purine and pyrimidine molecules for DNA replication, RNA synthesis, and cellular bioenergetics. Increased nucleotide metabolism supports uncontrolled growth of tumors and is a hallmark of cancer. Agents inhibiting synthesis and i...
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| Veröffentlicht in: | Mol Metab |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7096759/ https://ncbi.nlm.nih.gov/pubmed/32244187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.02.005 |
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