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ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance

The predominant way in which conventional chemotherapy kills rapidly proliferating cancer cells is the induction of DNA damage. However, chemoresistance remains the main obstacle to therapy effectivity. An increasing number of studies suggest that epithelial-to-mesenchymal transition (EMT) represent...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Drápela, Stanislav, Bouchal, Jan, Jolly, Mohit Kumar, Culig, Zoran, Souček, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096573/
https://ncbi.nlm.nih.gov/pubmed/32266287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00036
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