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ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma

Long-chain acyl-CoA dehydrogenase (ACADL) is a mitochondrial enzyme that catalyzes the initial step of fatty acid oxidation, but the role of ACADL in tumor biology remains largely unknown. Here, we found that ACADL was frequently downregulated in hepatocellular carcinoma (HCC), and its low expressio...

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Detalhes bibliográficos
Publicado no:NPJ Precis Oncol
Main Authors: Zhao, Xiaofang, Qin, Wenhao, Jiang, Youhai, Yang, Zhishi, Yuan, Bo, Dai, Rongyang, Shen, Hao, Chen, Yao, Fu, Jing, Wang, Hongyang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096519/
https://ncbi.nlm.nih.gov/pubmed/32219176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-0111-4
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