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Combined deletions of IHH and NHEJ1 cause chondrodystrophy and embryonic lethality in the Creeper chicken

The Creeper (Cp) chicken is characterized by chondrodystrophy in Cp/+ heterozygotes and embryonic lethality in Cp/Cp homozygotes. However, the genes underlying the phenotypes have not been fully known. Here, we show that a 25 kb deletion on chromosome 7, which contains the Indian hedgehog (IHH) and...

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Detalhes bibliográficos
Publicado no:Commun Biol
Principais autores: Kinoshita, Keiji, Suzuki, Takayuki, Koike, Manabu, Nishida, Chizuko, Koike, Aki, Nunome, Mitsuo, Uemura, Takeo, Ichiyanagi, Kenji, Matsuda, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096424/
https://ncbi.nlm.nih.gov/pubmed/32214226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0870-z
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