SKP1 drives the prophase I to metaphase I transition during male meiosis

The meiotic prophase I to metaphase I (PI/MI) transition requires chromosome desynapsis and metaphase competence acquisition. However, control of these major meiotic events is poorly understood. Here, we identify an essential role for SKP1, a core subunit of the SKP1–Cullin–F-box (SCF) ubiquitin E3...

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Udgivet i:Sci Adv
Main Authors: Guan, Yongjuan, Leu, N. Adrian, Ma, Jun, Chmátal, Lukáš, Ruthel, Gordon, Bloom, Jordana C., Lampson, Michael A., Schimenti, John C., Luo, Mengcheng, Wang, P. Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096161/
https://ncbi.nlm.nih.gov/pubmed/32232159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz2129
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