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Repression of Nrf2/ARE Regulated Antioxidant Genes and Dysregulation of the Cellular Redox Environment by the HIV Transactivator of Transcription

Chronic HIV infection in the era of anti-retroviral therapy is associated with dramatically increased risk of developing severe cardio pulmonary disease. Common to these diseases is increased oxidative burden and chronic inflammation despite low viremia and restoration of CD4+ T-cell levels. Soluble...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Simenauer, Ari, Assefa, Betelhem, Rios-Ochoa, Jose, Geracia, Kara, Hybertson, Brooks, Gao, Bifeng, McCord, Joe, Elajaili, Hanan, Nozik-Grayck, Eva, Cota-Gomez, Adela
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096131/
https://ncbi.nlm.nih.gov/pubmed/31238128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.06.015
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