Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus infection in macaques

The primary cause of severe acute respiratory syndrome (SARS) is a newly discovered coronavirus(1,2,3,4,5,6,7). Replication of this SARS coronavirus (SCV) occurs mainly in the lower respiratory tract, and causes diffuse alveolar damage(2,7,8). Lack of understanding of the pathogenesis of SARS has pr...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Haagmans, Bart L, Kuiken, Thijs, Martina, Byron E, Fouchier, Ron A M, Rimmelzwaan, Guus F, van Amerongen, Geert, van Riel, Debby, de Jong, Ton, Itamura, Shigeyuki, Chan, Kwok-Hung, Tashiro, Masato, Osterhaus, Albert D M E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095986/
https://ncbi.nlm.nih.gov/pubmed/14981511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1001
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