Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome by protecting against glycocalyx damage and suppressing inflammatory signaling pathways

OBJECTIVE: To explore the mechanisms of crocin against glycocalyx damage and inflammatory injury in lipopolysaccharide (LPS)-induced acute respiratory distress syndrome (ARDS) mice and LPS-stimulated human umbilical vein endothelial cells (HUVECs). METHODS: Mice were randomly divided into control, L...

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Veröffentlicht in:Inflamm Res
Hauptverfasser: Zhang, Dong, Qi, Bo-yang, Zhu, Wei- wei, Huang, Xiao, Wang, Xiao-zhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2020
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Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095881/
https://ncbi.nlm.nih.gov/pubmed/31925528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-019-01314-z
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