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Engineered Bone for Probing Organotypic Growth and Therapy Response of Prostate Cancer Tumoroids in vitro

Mechanistic analysis of metastatic prostate cancer (PCa) biology and therapy response critically depends upon clinically relevant three-dimensional (3D) bone-like, organotypic culture. We here combine an engineered bone-mimetic environment (BME) with longitudinal microscopy to test the growth and th...

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Pubblicato in:Biomaterials
Autori principali: Paindelli, Claudia, Navone, Nora, Logothetis, Christopher J., Friedl, Peter, Dondossola, Eleonora
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094882/
https://ncbi.nlm.nih.gov/pubmed/30682644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.01.027
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