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Humoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDL

Atherosclerosis is a chronic inflammatory disease and major cause of mortality worldwide. One of the crucial steps for atherosclerotic plaque development is oxidation of low-density lipoprotein (LDL). Through the oxidation, highly immunogenic epitopes are created and the immune system is activated....

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Pubblicato in:PLoS One
Autori principali: Kyrklund, Mikael, Bildo, Mika, Akhi, Ramin, Nissinen, Antti E., Pussinen, Pirkko, Hörkkö, Sohvi, Wang, Chunguang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094845/
https://ncbi.nlm.nih.gov/pubmed/32210456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230682
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