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ORF8a of SARS-CoV forms an ion channel: Experiments and molecular dynamics simulations
ORF8a protein is 39 residues long and contains a single transmembrane domain. The protein is synthesized using solid phase peptide synthesis and reconstituted into artificial lipid bilayers that forms cation-selective ion channels with a main conductance level of 8.9 ± 0.8 pS at elevated temperature...
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| Publicado no: | Biochim Biophys Acta Biomembr |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier B.V.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094593/ https://ncbi.nlm.nih.gov/pubmed/20708597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.08.004 |
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