In vitro activity of cepharanthine hydrochloride against clinical wild-type and lamivudine-resistant hepatitis B virus isolates

Hepatitis B virus (HBV) infection causes major public health problems worldwide. The clinical limitation of current antiviral drugs for HBV, such as lamivudine, is the emergence of drug-resistant viral strains during prolonged antiviral therapy. Cepharanthine hydrochloride (CH), a natural alkaloid-d...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Zhou, Yu-Bing, Wang, Ya-Feng, Zhang, Yan, Zheng, Li-Yun, Yang, Xiao-Ang, Wang, Ning, Jiang, Jin-Hua, Ma, Fang, Yin, De-Tao, Sun, Chang-Yu, Wang, Qing-Duan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094493/
https://ncbi.nlm.nih.gov/pubmed/22387093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.02.030
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