Knocking Down TcNTPDase-1 Gene Reduces in vitro Infectivity of Trypanosoma cruzi

Ecto-Nucleoside Triphosphate Diphosphohydrolases are enzymes that hydrolyze tri- and/or diphosphate nucleosides. Evidences pointed out to their participation in Trypanosoma cruzi virulence, infectivity, and purine acquisition. In this study, recombinant T. cruzi knocking out or overexpressing the Tc...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Silva-Gomes, Natália Lins, Rampazzo, Rita de Cássia Pontello, Moreira, Claudia Maria do Nascimento, Porcino, Gabriane Nascimento, dos Santos, Cyndia Mara Bezerra, Krieger, Marco Aurélio, Vasconcelos, Eveline Gomes, Fragoso, Stenio Perdigão, Moreira, Otacilio C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094052/
https://ncbi.nlm.nih.gov/pubmed/32256481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00434
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