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Phase 2 trial of montelukast for prevention of pain in sickle cell disease

Cysteinyl leukotrienes (CysLTs) are lipid mediators of inflammation. In patients with sickle cell disease (SCD), levels of CysLTs are increased compared with controls and associated with a higher rate of hospitalization for pain. We tested the hypothesis that administration of the CysLT receptor ant...

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Pubblicato in:Blood Adv
Autori principali: Field, Joshua J., Kassim, Adetola, Brandow, Amanda, Embury, Stephen H., Matsui, Neil, Wilkerson, Karina, Bryant, Valencia, Zhang, Liyun, Simpson, Pippa, DeBaun, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094028/
https://ncbi.nlm.nih.gov/pubmed/32208487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001165
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