Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E

BACKGROUND: Several lines of evidence suggest that high-density lipoprotein (HDL) reduces Alzheimer’s disease (AD) risk by decreasing vascular beta-amyloid (Aβ) deposition and inflammation, however, the mechanisms by which HDL improve cerebrovascular functions relevant to AD remain poorly understood...

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Publicat a:Mol Neurodegener
Autors principals: Robert, Jerome, Button, Emily B., Martin, Emma M., McAlary, Luke, Gidden, Zoe, Gilmour, Megan, Boyce, Guilaine, Caffrey, Tara M., Agbay, Andrew, Clark, Amanda, Silverman, Judith M., Cashman, Neil R., Wellington, Cheryl L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093966/
https://ncbi.nlm.nih.gov/pubmed/32213187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00366-8
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