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Visualization of cell-type dependent effects of anti-E2 antibody and interferon-gamma treatments on localization and expression of Broccoli aptamer-tagged alphavirus RNAs

Sindbis virus (SINV) is an alphavirus that causes age-dependent encephalomyelitis in mice. Within 7–8 days after infection infectious virus is cleared from neurons through the antiviral effects of antibody and interferon-gamma (IFNγ), but RNA persists. To better understand changes in viral RNA assoc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nilaratanakul, Voraphoj, Hauer, Debra A., Griffin, Diane E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093546/
https://ncbi.nlm.nih.gov/pubmed/32210257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61015-0
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