Lentiviral Vector Induced Modeling of High-Grade Spinal Cord Glioma in Minipigs

Background: Prior studies have applied driver mutations targeting the RTK/RAS/PI3K and p53 pathways to induce the formation of high-grade gliomas in rodent models. In the present study, we report the production of a high-grade spinal cord glioma model in pigs using lentiviral gene transfer. Methods:...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tora, Muhibullah S., Texakalidis, Pavlos, Neill, Stewart, Wetzel, Jeremy, Rindler, Rima S., Hardcastle, Nathan, Nagarajan, Purva P., Krasnopeyev, Andrey, Roach, Cristin, James, Raphael, Bruce, Jeffrey N., Canoll, Peter, Federici, Thais, Oshinski, John N., Boulis, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093438/
https://ncbi.nlm.nih.gov/pubmed/32210315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62167-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados